Pontifícia Universidade Católica de São Paulo - PUCSP
Abstract
We begin by a study case
on the use of quina at Teaching Hospital of University the Coimbra at the turn of the 19th century.
Next we discuss the isolation of cinchonine in Portugal and the polemics to which it gave rise
among scientists from Coimbra and Lisbon (1810-‐‑1812), as well as several of the most relevant
studies of quina and quinine conducted in Portugal at the turn of the 20th centuries. Finally, we
approach the problems posed by the cultivation of cinchona plants and quinine extraction in the
former Portuguese colonies