<div><p>(A) Genes expressed in temporally distinct subsets of progenitors. The first column shows relative SAGE tag levels for each gene under consideration. The UniGene identities and common names of the genes in question are <i>Mm.19155/sFrp2, Mm.3904/Fgf15, Mm.142856/Lhx2, Mm.35829/Edr,</i> and <i>Mm.22288/cyclin D1</i>. The sections for ISH and BrdU shown here were taken from near the center of the retina at the developmental times shown. Mice were albino Swiss Websters except in the case of the adults, which were pigmented C57B/6. See Table S5 for a full list of probes used. Cellular laminae of both the developing and mature retina are indicated with colored bars. All pictures were taken at 200x. The graph plotting the fraction of mitotic cells in the retina adjacent to the BrdU staining is an estimate based on data from both rat and mouse (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020247#pbio-0020247-Young1" target="_blank">Young 1985</a>a, <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020247#pbio-0020247-Young2" target="_blank">1985</a>b; <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020247#pbio-0020247-Alexiades1" target="_blank">Alexiades and Cepko. 1996</a>).</p>
<p>(B) Spatially heterogeneous ONBL. Genes that were expressed in spatial subsets of cells in the prenatal ONBL are shown. The genes shown are <i>Mm.4541/Sox2, Mm.18789/Sox4, Mm.4605/Tbx2, Mm.29067/Mbtd1, Mm.2229/Eya2, Mm.34701/Pum1, Mm.29924/Arl6ip1, Mm.11738/Ark-1, Mm.40321/Pgrmc2,</i> and <i>Mm.22288/cyclin D1</i>. Sections were from central retina. Cellular laminae of both the developing and mature retina are indicated with colored bars. All pictures were taken at 200x. See Table S5 for a full list of probes used.</p></div
