We construct a model of quark-lepton unification at the TeV scale based on an
SU(4) gauge symmetry, while still having acceptable neutrino masses and
enough suppression in flavor changing neutral currents. An approximate U(2)
flavor symmetry is an artifact of family-dependent gauge charges leading to a
natural realization of the CKM mixing matrix. The model predicts sizeable
violation of PMNS unitarity as well as a gauge vector leptoquark U1μ​=(3,1,2/3) which can be produced at the LHC -- both effects
within the reach of future measurements. In addition, recently reported
experimental anomalies in semi-leptonic B-meson decays, both in charged b→cτν and neutral b→sμμ currents, can be accommodated.Comment: 9 pages, 5 tables. Version accepted for publication in PL