The mechanical properties of brain tissue play a pivotal role in
neurodevelopment and neurological disorders. Yet, at present, there is no
consensus on how the different structural parts of the tissue contribute to its
stiffness variations. Here, we have gathered depth-controlled indentation
viscoelasticity maps of the hippocampus of isolated horizontal live mouse brain
sections. Our results confirm the highly viscoelestic nature of the material
and clearly show that the mechanical properties correlate with the different
morphological layers of the samples investigated. Interestingly, the relative
cell nuclei area seems to negatively correlate with the stiffness observed