Photomicrographs of spleen and liver sections from <i>Leishmania braziliensis</i> or <i>L. infantum</i> infected rodents stained with haematoxylin-eosin.

Abstract

<p>A: <i>L. braziliensis</i>-infected golden hamster (<i>Mesocricetus auratus</i>) 3 months post infection (mpi) – spleen revealed extensive necrosis and inflammation. Note necrotic focus containing amastigotes (arrows). B: <i>L. braziliensis</i>-infected <i>Thrichomys laurentius</i> (7289) 3 mpi – spleen showing architecture of red and white pulp, lack of parasites; C: <i>L. infantum</i>-infected <i>T. laurentius</i> (7548) 12 mpi (liver culture tissue positive) – panoramic view of the liver showing typical architecture with portal (PV) and central vein (CV); D: <i>L. infantum</i>- infected <i>T. laurentius</i> (7538), 12 mpi (liver culture tissue negative) – also illustrated liver showing normal architecture; E: <i>L. infantum</i>-infected <i>T. laurentius</i> (7548), 12 mpi (liver culture tissue positive) – overview of white and red pulp from spleen; F: <i>L. infantum</i>-infected <i>T. laurentius</i> (7538), 12 mpi (liver culture tissue negative) – also illustrated spleen overview of red and white pulp.</p