<p><b>(A,B)</b> The bottom and side views of the binding pocket residue and the ATP plus Mg<sup>2+</sup> (the sphere colored in blue) complex. The residue T433 (the fixed end), G431 (the hinge) and D429 (the gate) form the ATP gate <b>(B)</b>. Lock 1 is illustrated as twin-headed arrow with solid line, Lock 2 is illustrated as dashed line and Lock 3 is represented as dotted line. The bottom two rows of figures represent the views from the bottom and the side of the ATP binding pocket, showing the four key snapshots during ATP binding process, namely the Apo state, WS, TS and ATP bound state. The oxygen atoms near the gate are illustrated as red balls in the ATP bound state.</p
