<p><b>(A)</b> The C-α displacement of the tip residue H513 on the β hairpin. <b>(B)</b> The C-α displacement of the tip residue D455 on the central channel of the C-terminal. <b>(C)</b> The average folding angle of D2/D3, represented by the angle between C-α of LYS331, ASN366 and HIS513. <b>(D)</b> The average channel radius on the top (black), middle (red) and bottom section (blue). <b>(E)</b> The angle that can be changed between two domains (domain folding angle) is indicated (red arrow), C-α positions of the top K331, middle H513 and bottom D455 are shown in the helicase. The H513 and D455 displacements are shown in grey arrows.</p
