Provinols™ increase NO vascular release in vessels from ZF rats.

Abstract

<p>NO production in aorta (A), carotid arteries (B) and small mesenteric arteries (C) from Zucker fatty (ZF) and ZF+Provinols™ rats. Values are expressed as units of amplitude (A)/mg weight of dried tissue (dw). Western blots revealing expression of eNOS (D), phosphorylation of eNOS at Thr495 (E), and NOS Ser1177 (F) and expression of caveolin-1 (G) in aorta expressed as arbitrary units (A.U.). (<i>n</i> = 6). *<i>P</i><0.05, **<i>P</i><0.01 <i>vs.</i> ZF rats.</p