Representative Germline CNVs in Mice Identified by High-Resolution aCGH

Abstract

<div><p>The log₂ ratios of signal intensity for C57BL/6J (reference) versus 20 test strains are shown. Inset, an expanded view of the CNVs in NOD/LtJ and A/J from (A) and (B). Scale, 500 kb.</p><p>(A) A 135.6-kb segment of reduced copy number (mean log₂ = −1.02) on Chromosome 14 is present in most strains.</p><p>(B) A 61.7-kb amplified segment (mean log₂ = +1.01) on Chromosome 1 is present in most strains.</p></div