Effect of One Pulse of cAMP Followed by a Train of Ca²⁺ Spikes on DARPP-32 Phosphorylation

Abstract

<p>Time-course of DARPP-32 isoforms triggered by a pulse of cAMP followed by a train of Ca²⁺ spikes. Colour code of DARPP-32 isoforms is the same as for <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020176#pcbi-0020176-g003" target="_blank">Figure 3</a>. Relax and Thr34min show the two readouts used in sensitivity analysis. (A) model A; (B) model B.</p