The Eye Is a Transparent System That Permits Direct Visualization of Retinoblastoma

Abstract

<div><p>(A) Untreated retinoblastoma involving the macula of the left eye. The translucent cornea and lens allow detailed visualization. The tumor is an amelanotic, partially calcified mass that has broken through the overlying retina. Dilated arterioles infiltrate the tumor.</p> <p>(B) The same tumor after being treated with chemotherapy. The mass has completely calcified, and the caliber of the overlying retinal vessels has diminished. A focal area of atrophied retinal pigmented epithelium surrounds the lesion.</p></div