<p>Fold-change (<i>x</i>-axis) is plotted against the statistical significance (<i>y</i>-axis) for each probeset. Fold-changes are shown on log<sub>2</sub> scale. <i>p-</i>Values are shown on a negative log<sub>10</sub> scale. The symbol × indicates genes with reduced expression in <i>mec-3(e1338)</i> animals (fold-change < −1, <i>p</i> < 0.01). Light blue circles indicate genes with reduced expression that are also on Chromosome 4. Dark blue circles indicate genes with reduced expression that are within 1 cM to the left or right of <i>mec-3</i>. The open red circle indicates the <i>mec-3</i> gene.</p
