Abstract

<div><p>(A) Coverage of known mitochondrial proteins (Mref) by two MS proteome studies (this study and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020160#pbio-0020160-Sickmann1" target="_blank">Sickmann et al. [2003]</a>). We evaluated the 340 proteins of the mitochondrial reference set for which protein abundance data existed (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020160#pbio-0020160-Ghaemmaghami1" target="_blank">Ghaemmaghami et al. 2003</a>). The x-axis represents the median protein abundance of ten consecutive, equally sized bins of proteins.</p> <p>(B) Distribution and overlap of proteins identified by the two MS studies and known mitochondrial proteins. The total number of entries for each dataset is indicated in parentheses outside each circle. The number inside each circle indicates the number of proteins in each of the categories. In addition, the percentage of proteins that were localized to mitochondria by GFP tagging (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020160#pbio-0020160-Huh1" target="_blank">Huh et al. 2003</a>) is given in parentheses for each category.</p></div

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