Expression of FGFR1, FGFR3, and bFGF in distinct subsets of human BC cell lines.

Abstract

<p>A. Correlation of FGFR1 and FGFR3 with canonical EMT markers. mRNA levels were measured using whole genome mRNA expression profiling (Illumina platform). The heat map depicts the expression of FGFR1, FGFR3, FGF2 (bFGF), p63 (TP63), E-cadherin (CDH1), Slug (SNAI2), and vimentin. B. Quantitative analysis of EMT marker expression. Relative levels of the “epithelial” markers E-cadherin (CDH1) and p63, and the “mesenchymal’ markers ZEB1 and vimentin were measured by quantitative real-time RT-PCR.</p

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