<p>(a) Representative dot plots showing the gating strategy and sort purity of CD4<sup>+</sup>PD-1<sup>hi</sup> and CD4<sup>+</sup>PD-1<sup>β</sup> T cells. b) Fold change in expression of CXCR5 and IL-21 mRNA levels in CD4<sup>+</sup>PD-1<sup>hi</sup> T cells relative to CD4<sup>+</sup>PD-1<sup>β</sup> T cells. mRNA expression was determined <i>ex vivo</i> in sorted cells by relative qRT-PCR.</p