Null alleles of <i>ocm</i> results in decreased cell numbers in the fly eyes.

Abstract

<p>Different <i>ocm</i> alleles were assayed for cell viability in <i>Drosophila</i> eye. (A-B) <i>ocm<sup>S1590F</sup></i>, a weak hypomorphic allele of <i>ocm</i> does not affect cell growth. Other hypomorphic alleles, <i>ocm<sup>G1646E</sup></i> and <i>ocm<sup>V1286D</sup></i> were also tested but they are indistinguishable to <i>ocm<sup>S1590F</sup></i> (data not shown). Increasingly severe alleles (C–D) <i>ocm<sup>V1334D</sup></i>, (E–F) <i>ocm<sup>166</sup></i><sup>Δ<i>11 bp</i></sup> (null allele) result in fly eyes dramatically reduced in size.</p

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