Enantioselective Iron-Catalyzed Azidation of β‑Keto
Esters and Oxindoles
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Abstract
The first example of Fe-catalyzed
enantioselective azidations of
β-keto esters and oxindoles using a readily available N<sub>3</sub>-transfer reagent is reported. A number of α-azido-β-keto
esters were obtained with up to 93% ee, and this methodology also
generates 3-substitued 3-azidooxindoles with high enantioselectivities
(up to 94%)