Bacteria-Adsorbed Palygorskite Stabilizes the Quaternary
Phosphonium Salt with Specific-Targeting Capability, Long-Term Antibacterial
Activity, and Lower Cytotoxicity
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Abstract
In
order to extend the antibacterial time of quaternary phosphonium
salt in bacteria, palygorskite (PGS) is used as the carrier of dodecyl
triphenyl phosphonium bromide (DTP), and a DTP-PGS hybrid is prepared.
Antibacterial performance of this novel hybrid is investigated for
both Gram-positive and Gram-negative bacteria. The results show that
the DTP could be absorbed on the surface of PGS which had bacteria-adsorbed
capability. The DTP-PGS hybrid, combining the advantages of PGS and
DTP, display specific-targeting capability, long-term antibacterial
activity, and lower cytotoxicity, suggesting the great potential application
as PGS-based antibacterial powder