Stereodivergent Synthesis of (+)- and (−)-Isolineatin

Abstract

A stereodivergent approach to (+)- and (−)-isolineatin using (<i>S</i>)-4-methyl-5-pivaloyloxymethyl-2­(5<i>H</i>)-furanone as the single source of asymmetry by exploiting the inherent chirality at the C-5 stereocenter is described