Tumour uptake (A), tumour-to-blood ratios (B), and tumour-to-surrounding muscle ratios (C) of E3S.

Abstract

<p>Tumour uptake (A), tumour-to-blood ratios (B), and tumour-to-surrounding muscle ratios (C) of E3S in mice bearing MCF-7 (hormone dependent) and MDA-MB-231 (non-hormone dependent) xenografts expressed as % injected dose per gram (%ID/g) at 2 h, 6 h and 48 h p.i. Uptake of E3S/[³H]-E3S was significantly higher in hormone dependent MCF-7 xenografts at all time points. Statistically significant (<i>p</i><0.05) difference is also observed in the ratio of the tumour uptake and the surrounding muscle uptake between the two xenograft models. *<i>p</i><0.05, **<i>p</i><0.01.</p