Abstract

<p>(A) Conformational changes of the group II chaperonin in the absence (left) and presence (right) of ATP. (B) Schematic illustration of the detection of internal motions of group II chaperonins by DXT. (C) Typical DXT traces of gold nanocrystals immobilized on the ring of the group II chaperonin in the absence (upper panel) and presence of ATP (lower panel). (D) The distribution of the absolute angular displacement of the group II chaperonin in the twisting (χ) direction. About 500 DXT trajectories are used to make histogram. The trajectories with an angular displacement greater than 30 mrad in the χ direction were counted as inset bar-graph.</p

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