<p>(<b>a</b>). Total and average number of TFBSs present in the promoters of genes expressed in the HR subset. Frequencies were calculated on the genes clustered using the functional distance metric weighted by local density and TF similarity. In bold are shown TFs (Oct-1 and NF-KAPPA B) with an average number value exceeding 2 sites/promoter. (<b>b</b>). Analysis of localization within clusters of HR genes having the signature of immune/inflammatory response. The <i>Show dataset into clusters</i> utility of CluGene (top panel), allows to identify which clusters (red) out of the total (blue) contain a specified list of genes (immune annotated genes). The list of genes contained in clusters and their location is given on the right part of the panel. The tables (bottom) include the identified clustered immunity genes (bold), their function and the size and what other genes are grouped within the same cluster.</p