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Dabrafenib structure and activity against RAF kinases.
Authors
Alastair J. King (430098)
Angela Hughes-Earle (430106)
+13Â more
David E. Uehling (430111)
Hongwei Qi (430109)
Jingsong Yang (430102)
Joseph A. Erhardt (430105)
Katherine G. Moss (430101)
Kelly E. Fedorowicz (430103)
Kimberly N. Smitheman (430104)
Laurie S. Kane-Carson (430107)
Marc R. Arnone (430099)
Maureen R. Bleam (430100)
Robert H. Sinnamon (430108)
Sylvie G. Laquerre (430112)
Tara R. Rheault (430110)
Publication date
Publisher
Doi
Cite
Abstract
<p>Dabrafenib chemical structure (A). Dabrafenib potency (IC<sub>50</sub>) was measured against the kinase activity of various BRAF orthologs, human BRAF mutants, and human CRAF (B).</p
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Last time updated on 12/02/2018