<p>VSMC from SHR and WKY rats were incubated in the absence (control) or presence of various concentrations of C-ANP<sub>4–23</sub> (A), NSC 625987 (B) or NU2058 (C) for 16 h. Thymidine incorporation was determined as described in “<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0076183#s2" target="_blank">Methods</a>”. Results are expressed as % of WKY CTL, taken as 100%. Values are means ± SE of 5 separate experiments. *** <i>P</i><0.01, ***<i>P</i><0.001 vs WKY CTL, #<i>P</i><0.05, ##<i>P</i><0.01 vs SHR CTL.</p
