<i>M. bovis</i> BCG inhibits IL-2 induced proliferation of CD56<sup>bright</sup> NK cells.

Abstract

<p>A) Purified NK cells from a healthy human donor were labelled with CFSE and cultured for 7 days in the presence of IL-2 (100U/ml) +/- <i>M. bovis</i> BCG at various MOI before flow cytometry analysis. Dose dependent inhibition of NK cell proliferation by mycobacteria was observed. B) Joined dot plot illustrating the reproducibility of NK cell proliferation inhibition by mycobacteria across different NK cell preparation across independent donors (n=4, paired t test, **p<0.01).</p

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