Memory of Chirality Approach to the Enantiodivergent Synthesis of Chiral Benzo[<i>d</i>]sultams

Abstract

The “memory of chirality” stereodivergent synthesis of polyfluorobenzo[<i>d</i>]sultams has been developed. The interest of this protocol resides in the possibility of using the chirality of a starting sulfonamide single enantiomer to synthesize the target sultams in both absolute configurations, by using different base systems, under homogeneous conditions