Enantioselective Total Syntheses of Pygmaeocins B
and C
- Publication date
- Publisher
Abstract
The first enantioselective total syntheses of pygmaeocins B and
C have been accomplished using an efficient and highly diastereoselective
intramolecular Heck cyclization for the construction of a quaternary
stereogenic center and the functionalized A-ring of the natural products
as the key step