BTG3 is down-regulated in clinical paraffin-embedded HCC tissues and a prognostic factor for poor overall survival in HCC patients.

Abstract

<p>(A) Strong positive expression of BTG3 in adjacent normal livers (×200, ×400). (B) Positive expression of BTG3 in the cirrhotic livers (×100, ×400). (C) Negative expression of BTG3 in HCC tissues compared with strong positive expression in adjacent livers (×200, ×400). (D) Week expression of BTG3 in HCC tissues while strong positive expression in adjacent livers (×200, ×400). (E) Negative expression of BTG3 in HCC tissues with low differentiation (×200, ×400). (F) Weak expression of BTG3 in HCC tissues with high differentiation (×200, ×400). (G) Kaplan-Meier survival analysis of primary HCC patients with high and low BTG3 expressions.</p

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