<p>Confocal images of embryos expressing GFP-tubulin and mCherry-histone are shown. The posterior of the embryos are to the right. The control embryo treated with 5% DMSO divided normally. The white arrowhead points to the microtubule fibres, which were observed in all embryos before drug addition. Embryos treated with nocodazole and paclitaxel did not divide and microtubule fibres were seen in the time frame before drug addition indicated by white arrowheads. In nocodazole-treated embryo, fluorescence was visible only at the centrosomes (white arrows) and the centrosomes gradually drifted towards each other. In paclitaxel treated embryos, white arrows indicate tubulin aggregates in the cytoplasm.</p
