<p>Effect of (<b>A</b>) temperature range of hypothermia induction, (<b>B</b>) time of hypothermia administration, (<b>C</b>) duration of hypothermia and, (<b>D</b>) experimental cotreatment on the effect size reported within experiments employing regional hypothermia. The shaded gray bar represents the 95% confidence limits of the global estimate. The vertical error bars represent the 95% confidence intervals for the individual estimates. The width of each bar reflects the log of the number of animals contributing to that comparison. Each stratification accounts for a significant proportion of the heterogeneity observed between studies.</p
