Abstract

<p>Exudate peritoneal cells were isolated from the treated nondiabetic <i>Apoe</i><sup>−/−</sup> mice (a) or diabetic <i>Apoe</i><sup>−/−</sup> mice (b) at 21 weeks of age, or <i>db/db</i> diabetic mice (c) at the age of 13 weeks, 4 days after an intraperitoneal injection of thioglycolate. Adherent macrophages were incubated for 18 hours with the RPMI-1640 medium containing 10 μg/ml oxLDL in the presence of 0.1 mmol/l [<sup>3</sup>H]oleate conjugated with bovine serum albumin. Cellular lipids were extracted and the radioactivity of the cholesterol [<sup>3</sup>H]oleate was determined by thin-layer chromatography. *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001.</p

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