Levels of RIND-EDSBs in yeast strains with deletions of genes encoding proteins with the High-Mobility Group B (HMGB) domain.

Abstract

<p>The levels of EDSBs were significantly decreased in G0 cells of yeast strains lacking <i>NHP6A</i>, <i>IXR1</i>, <i>ROX1</i>, and <i>HMO1</i>, suggesting that they play an important role in the production or retention of RIND-EDSBs. Nevertheless, the levels of RIND-EDSBs in <i>nhp6b</i>Δ, <i>nhp10</i>Δ, and <i>abf2</i>Δ strains were unchanged. The levels of EDSBs from 9 independent experiments are shown as box plots, with the boxes representing the interquartile ranges (25^th to 75^th percentile) and the median lines representing the 50^th percentile. The whiskers represent the minimum and the maximum values. <i>**P</i><0.001 (Mann-Whitney test).</p