Anxiety-related and activity measures in the open field test.

Abstract

<p>All four experimental groups from the FCG cross spent an equal amount of time in the aversive central portion of the arena (<b>A</b>), made equal numbers of entries into this area (<b>B</b>), and showed equal latencies in making the first entry into this zone (<b>C</b>). There was a significant interaction between SRY DEPENDENCE and SEX CHROMOSOME COMPLEMENT on activity within the open field, consistent with gonadally female mice with an XX karyotype being more active than gonadally female mice with an XY karyotype, and gonadally male mice with an XY karyotype being more active than gonadally male mice with an XX karyotype (<b>D</b>).</p

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