Clustering analysis of the miRNA with altered expression levels in epileptic animals.

Abstract

<p>(<b>A</b>) Clusters represent groups of miRNAs displaying similar alterations in expression over time after stimulation. Colors of lines within the clusters indicate the membership values of the expression profile to current cluster. Red and violet are high membership values and blue and green are low membership values. Members of each cluster are listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0076051#pone.0076051.s001" target="_blank">Table S1</a>. (<b>B</b>) Functional analysis of miRNA belonging to individual clusters. Functions associated with top networks according to Ingenuity Pathways are listed. (<b>C</b>) Functions belonging to “Neurological Disorder” and “Nervous System Development and Function” categories as defined by Ingenuity Pathways in individual miRNA clusters. Functions related to brain cancer and tumors are not included. Lists of functions with respective miRNAs are presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0076051#pone.0076051.s002" target="_blank">Table S2</a>.</p

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