<p>Lethally irradiated CD45.1<sup>+</sup> wt mice were reconstituted with CD45.2<sup>+</sup> wt or Siglec-H<sup>−/−</sup> BM followed by infection with 5×10<sup>4</sup> PFU of wt MCMV. (<b>A</b>) FACS plots show efficient donor reconstitution in the blood eight weeks after BM transfer (upper panel). Siglec-H and B220 stainings of splenocytes confirm the lack of Siglec-H expression in wt mice reconstituted with Siglec-H<sup>−/−</sup> BM (lower panel). (<b>B</b>) The kinetics of serum IFNα levels 1.5, 3 and 6 days p.i. compared between Siglec-H<sup>−/−</sup> and wt mice, n = 4–5 mice/group. Data are from one of two individual experiments with similar results. ns = not significant ***<i>p</i><0.001, Students t-test.</p
