<p>Effect of exogenous rUII (6 pmol. min<sup>-1</sup>. 100 g bwt<sup>-1</sup>, solid bars, n = 7 per strain), URP (6 pmol. min<sup>-1</sup>. 100 g bwt<sup>-1</sup>, hatched bars, n = 5 per strain) or vehicle (0.154 mol/L NaCl, open bars, n = 6 per strain) infusion on mean arterial pressure (A-B), effective renal blood flow (C-D) and glomerular filtration rate (E-F) in anaesthetised 4-5 week-old WKY rats (left column) and pre-hypertensive SHRs (right column). Data shown are mean ± SEM for the baseline control period and the final 15 mins of the treatment period when effects were maximal. * P < 0.05, ** P < 0.01 compared with vehicle-treated rats, Dunnett’s test.</p