<p>Mice were i.m. vaccinated with formalin inactivated RSV A2, rested for at four weeks and i.n challenged with either live RSV A2 (FI-A2+A2), UV-inactivated RSV A2 (FI-A2+UV-A2) or unifected vero cell lysate (FI-A2+vero). Unimmunized mice challenged with live RSV A2 (A2) provide a comparison to results after acute infection. Unvaccinated RSV challenged mice are compared to FI-RSV vaccinated mice challenged with live RSV mice and to FI-RSV vaccinated mice challenged with UV-inactivated RSV A2. Data from a separate experiment compares the inflammatory responses to FI-RSV vaccinated and vero cell lysate challenged mice. On day 5 post-infection, total BAL cell counts (A), total eosinophil counts (B) and viral RSV M gene mRNA (C) in the lungs of mice were determined. Total eosinophil counts were calculated by multiplying the total BAL cell counts by the percent eosinophils and presented as total eosinophils in BAL. Significance was calculated using a Student's <i>t</i> test, comparing mice in each group to mice vaccinated with FI-A2 alone and then challenged with RSV . * <i>p</i><0.05 A2 compared to FI-A2+UV-A2 or FI-A2+vero; ** <i>p</i><0.05 significance FI-A2 + A2 compared to either A2 or FI-A2+UV-A2 or FI-A2+vero. ND= not detected.</p
