Number of elite controllers (EC), their proportion, and demographic characteristics applying the CASCADE dataset to 10 definitions of EC found in the literature.

Abstract

†<p>Individuals in the cohort without adequate follow-up or number of HIV-RNA measurements to classify them as EC or non-EC.</p>‡<p>Based on number of seroconverters whose EC status could be determined.</p><p>HIV risk groups: MSM: Men who have sex with men; IDU: Injection drug users; MSW: Heterosexual contact.</p><p>Assuming all individuals with unknown EC status are non-EC.</p>ŧ<p><b>A</b>: HIV-positive ≥6 months, with ≥2 consecutive HIV-RNA <75 copies/ml; <b>B</b>: HIV- positive ≥1 year, with ≥1 HIV-RNA <50 copies/ml, <b>C</b>: HIV- positive ≥1 year, with ≥1 HIV-RNA <75 copies/ml, <b>D</b>: HIV- positive ≥1 year, with ≥3 HIV-RNA <2000 copies/ml, <b>E</b>: HIV- positive ≥1 year, with ≥3 consecutive HIV-RNA <75 copies/ml spanning ≥12 months <b>F</b>: HIV- positive ≥1 year, with ≥3 consecutive HIV-RNA <75 copies/ml spanning ≥12 months with no previous blips ≥1000 copies/ml, <b>G</b>:HIV- positive ≥2 years, with ≥2 HIV-RNA <75 copies/ml, <b>H</b>: HIV- positive ≥5 years, with ≥5 consecutive HIV-RNA <500 copies/ml, <b>I</b>: HIV- positive ≥10 years, with all measured HIV-RNA <50 copies/ml, <b>J</b>: HIV-positive ≥10 years, with ≥90% of HIV-RNA (≥2 HIV-RNA ever) <400 copies/ml.</p

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