Abstract

<p>BioPAX (BP) Prior s a tool for people who work with proteomics data and want to conduct pathway-context aware analysis. Given a set of annotated protein states, (such as phosphorylations, active/inactive tags and concentration levels), this programs creates a map from the input states onto the Pathway Commons 2 entities and finds the minimum distance between them -- the distances are extracted from BioPAX graphs. The ouput, so called prior information network, is a tab-limited file in Simple Interaction Format and it contains:</p> <p>- Source/target entities</p> <p>- Directional distance measure between these two entities</p> <p>- Pubmed IDs associated with links as external references</p> <p>- Reactions and their types included in the path between two entities.</p

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