<p>a (model 2) Adjusted for age, gender, smoking status, alcohol drinking behavior, regular exercise, hypertension, increased low-density lipoprotein cholesterol, decreased high-density lipoprotein cholesterol, hypertriglyceridemia, hyperuricemia, diabetes mellitus, urine occult blood, hemoglobin and preserved eGFR at baseline.</p><p>b (model 3) Adjusted for model 2 plus body mass index. Cox proportional-hazards models were used to calculate hazard ratios and 95% confidence intervals. Definitions of these confounding factors are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0088873#pone-0088873-t001" target="_blank">Table 1</a>.</p><p>WheiR, waist to height ratio; CI, confidence interval; Q1, lowest quartiles; Q2, second quartiles; Q3, third quartiles; Q4, highest quartiles.</p