Rhodium(III)-Catalyzed C–C Coupling of Arenes with 2‑Vinyloxiranes: Synthesis of Allylic Alcohols

Abstract

A rhodium­(III)-catalyzed C–C coupling between 2-vinyloxiranes and arenes directed by different chelating groups has been realized via a C–H activation pathway. This reaction proceeded under conditions with a low catalyst loading, and allylic alcohols were isolated as the coupling products. A series of benzoazepanes has been synthesized by following this coupling