Immunohistochemical characteristics of representative frozen sections of aortic roots from <i>Ldlr<sup>−/−</sup>Apob</i><sup>100/100</sup><i>Mttp</i><sup>flox/flox</sup> and <i>Ldlr<sup>−/−</sup>Apob</i><sup>100/100</sup><i>Mttp</i><sup>Δ/Δ</sup> mice.
<p>(A–C) Average percent stained area of total aortic root area (right) and representative stained aortic roots (left). Bars indicate SD. Original magnification, 50×. *<i>P</i><0.05, **<i>P</i><0.01, and ***<i>P</i><0.001. (A) Oil-Red-O staining (n = 6–9 per group). (B) CD68 staining (n = 5–8 per group). (C) Sirius Red staining (collagen) (n = 3 per group). (D) Mean plaque stability score (arbitrary units). Bars indicate SD. Average plaque stability scores were divided by total extent of plaque burden to assess stability per mouse (not individual plaques). Inset: magnifications of plaque stability score/mouse at 30, 40, 50, and 60 weeks before regression.</p
