Boron Trifluoride Etherate Functioning as a Fluorine
Source in an Iodosobenzene-Mediated Intramolecular Aminofluorination
of Homoallylic Amines
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Abstract
A widely used Lewis acid BF<sub>3</sub>路Et<sub>2</sub>O was
shown to be capable of acting as an efficient fluorinating agent in
an intramolecular aminofluorination reaction of homoallylic amines
to provide 3-fluoropyrrolidines mediated by a commercially available
hypervalent iodine颅(III) reagent PhIO at room temperature. A mechanism
involving a carbocation intermediate was proposed on the basis of
several experimental evidence
