Antimicrobial activity and chemical analysis of <i>Microlicia hatschbachii</i> Wurdack (Melastomataceae) extract

Abstract

<div><p>Aerial parts of <i>Microlicia hatschbachii</i> were extracted with hexane, and the extract was evaluated for antimicrobial activity by a broth dilution method. After phytochemical procedures: GC-MS identified aliphatic alkanes, carboxylic acids and methyl esters of long-chain fatty acids; and two diterpenoids [labd-8(17)-en-15-oic acid and labd-8(17),13-dien-15-oic acid] were identified by <sup>1</sup>H and <sup>13</sup>C NMR. The antimicrobial activity of the hexane extract could be attributed to the presence of labdanes. This identification is the first reported occurrence of labdane diterpenes in the Melastomataceae family.</p></div

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