<p>Individuals correspond to those shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091598#pone-0091598-g001" target="_blank">Fig. 1</a>.</p><p>i-phosphate: inorganic phosphate; SD: standard deviation; F: female; M: male; and N.E.: not examined.</p>a<p>Reference values: calcium, 9.0–11.0 mg/dL in infants and 8.8–10.2 mg/dL in adults; inorganic phosphate, 4.8–7.5 mg/dL in infants and 2.5–4.5 mg/dL in adults, and intact PTH, 10–65 pg/dL in infants and 14–55 pg/dL in adults.</p><p>Conversion factor to the SI unit: 0.25 for calcium (mmol/L), 0.32 for inorganic phosphate (mmol/L), and 0.106 for intact PTH (pmol/L).</p>b<p>Examined by echocardiography, chest roentgenography, and/or electrocardiography.</p>c<p>Examined by computed tomography.</p>d<p>Received velopharyngeal closure.</p>e<p>On treatment with vitamin D.</p>f<p>Repeated otitis media only.</p>g<p>Received speech therapy.</p>h<p>Required hearing aids.</p>i<p>At the time of diagnosis (11 years of age), serum TSH was <0.01 mIU/L, free T<sub>3</sub> 33.1 pg/mL [51.0 pmol/L], free T<sub>4</sub> 5.11 ng/dL [65.8 nmol/L], and TSH receptor antibody 1284% [normal range <1.9%].</p
