Effect of nicotine (0.5–4 mg/kg/day, 2 weeks) on areas under the curves (AUC, %vasodilation.nmol) of the cumulative renal vasodilatory effect of acetylcholine (0.01–2.43 nmol), NECA (1.6–50 nmol), and papaverine (1–2.43 nmol) in phenylephrine (10 µM)-preconstricted isolated perfused kidneys obtained from sham rats.

Abstract

<p>Values are means±S.E.M. of 6–8 observations. ^*P<0.05 vs. saline values.</p