DMF as a Source of Oxygen and Aminomethine: Stereoselective
1,2-Insertion of Rhodium(II) Azavinyl Carbenes into the CO
Bond of Formamides for the Synthesis of <i>cis</i>-Diamino
Enones
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Abstract
A new catalytic reaction in which
all the atoms of a formamide
are incorporated into the product through a formal stereoselective
1,2-insertion of rhodium(II) azavinyl carbenes, generated in situ
from readily available <i>N</i>-sulfonylated 1,2,3-triazoles,
into the CO bond of DMF and other <i>N</i>,<i>N</i>-disubstituted formamides to afford <i>cis</i>-diamino enones is described