<p>CCT2-knockdown (+) or control-knockdown (−) HepG2 cells were immunoblotted for pStat3 and total Stat3 (tStat3) 30 min after incubation in media alone or in media containing IL-6 at the indicated concentrations. Representative immunoblots are shown in the top panel. Densitometry readings of the immunoblot bands were normalized to the IL-6 concentration yielding maximum pStat3 levels (1 ng/ml) in two experiments. The ratios of densitometry values (pStat3/tStat3) for these experiments is shown in the bottom panel; results in CCT2 knockdown cells that are indicated with an asterisk (*) differ from control knockdown cells (<i>p</i><0.05).</p
