Polypyrrole-Coated
Chainlike Gold Nanoparticle Architectures
with the 808 nm Photothermal Transduction Efficiency up to 70%
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Abstract
Aqueous Au nanoparticles (NPs) are
employed as the building blocks
to construct chainlike self-assembly architectures, which greatly
enhance the photothermal performance at 808 nm. Biocompatible polypyrrole
(PPy) is further adopted as the package material to coat Au NP chains,
producing stable photothermal agents. As a result
of contributions from chainlike Au, the PPy shell, as well as the
Au–PPy composite structures, the capability of photothermal
transduction at 808 nm is greatly enhanced, represented by the high
photothermal transduction efficiency up to 70%. Primary animal experiment
proves that the current composite photothermal agents are efficient
in inhibiting tumor growth under an 808 nm irradiation, showing the
potentials for in vivo photothermal therapy