<p><i>Note</i>: All participants in the alcohol dependent group met DSM-IV criteria for alcohol dependence but had undergone monitored abstinence prior to participating. Severity of alcohol dependence was measured with the Alcohol Dependence Scale <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094640#pone.0094640-Skinner1" target="_blank">[62]</a>. All daily smokers met criteria for nicotine dependence. Family history reflects alcoholism in any first- or second-degree relatives. Groups did not differ significantly for any demographic characteristics. N/A: other than confirming the absence of alcohol use disorders, we did not assess drinking behavior and drinking history in the healthy control group.</p